hCG-secreting malignancies – diagnostic pitfalls

ACTH-dependent Cushing's Syndrome: Diagnostic Pitfalls in Concomitant Non-secreting Pituitary Adenomas

Objectives: To describe the possible pitfalls in correctly interpreting clinical, radiological and biochemical findings in ACTH-dependent Cushing's syndrome. Methods: We describe a case of a pituitary adenoma visualized at MRI not correlated with an ACTH-dependent Cushing’s syndrome. Results: Radiological imaging and hormonal testing can be misleading in suspected pituitary ACTH-related Cushing...

Diagnostic pitfalls of pilomatricoma on fine needle aspiration cytology

Pilomatricoma is a benign skin adnexal tumour usually seen in the head and neck region of children and young adults. It is underrecognized on cytology, resulting in the overdiagnosis of malignancy. We bring forth a case report of a slow growing nodular swelling in a 10-year-old female child, which was misdiagnosed on Fine Needle Aspiration Cytology (FNAC) as a malignant neoplasm and found to be...

Diagnostic success with pitfalls.

Rare lymphoid malignancies of the breast: a report of two cases illustrating potential diagnostic pitfalls

Breast involvement by lymphoma is uncommon and poses challenges in diagnosis. Lymphomas may clinically, radiologically, and morphologically mimic both benign and neoplastic conditions. We describe two cases of lymphoid malignancies predominantly involving the breast, both presenting diagnostic dilemmas. The first case, ALK-negative anaplastic large-cell lymphoma involving a seroma associated wi...

Pitfalls in the diagnosis of haematological malignancies

Increased knowledge of the immunophenotypic, cytogenetic and molecular heterogeneity of haematological diseases has challenged the traditional approach to disease classification based on morphology. In the current WHO classification, an integrated approach combining clinical details, morphology, immunophenotyping and genetic features is used for the diagnosis of haematological malignancies. An ...